ARHGDIG

Rho GDP-dissociation inhibitor 3 is a protein that in humans is encoded by the ARHGDIG gene.^[5][6][7]

ARHGDIG
Identifiers
Aliases	ARHGDIG, RHOGDI-3, Rho GDP dissociation inhibitor gamma
External IDs	OMIM: 602844; MGI: 108430; HomoloGene: 7337; GeneCards: ARHGDIG; OMA:ARHGDIG - orthologs
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16p13.3 Start 280,450 bp[1] End 283,010 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17|17 A3.3 Start 26,418,157 bp[2] End 26,426,760 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right hemisphere of cerebellum right frontal lobe body of pancreas cingulate gyrus anterior cingulate cortex Brodmann area 9 amygdala prefrontal cortex nucleus accumbens gonad Top expressed in nasal epithelium olfactory epithelium superior frontal gyrus dentate gyrus of hippocampal formation granule cell stomach primary visual cortex olfactory bulb prefrontal cortex neural tube striatum of neuraxis More reference expression data BioGPS More reference expression data
Gene ontology Molecular function GDP-dissociation inhibitor activity Rho GDP-dissociation inhibitor activity protein binding GTPase regulator activity GTPase activator activity Cellular component cytoplasm membrane cytoplasmic vesicle cytosol plasma membrane Biological process negative regulation of cell adhesion positive regulation of GTPase activity regulation of catalytic activity regulation of small GTPase mediated signal transduction Rho protein signal transduction regulation of protein localization blastocyst hatching Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 398 14570 Ensembl ENSG00000242173 ENSMUSG00000073433 UniProt Q99819 Q62160 RefSeq (mRNA) NM_001176 NM_008113 RefSeq (protein) NP_001167 NP_032139 Location (UCSC) Chr 16: 0.28 – 0.28 Mb Chr 17: 26.42 – 26.43 Mb PubMed search [3] [4]
Wikidata
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Interactions

ARHGDIG has been shown to interact with RHOB.^[8]