ATG9B

Autophagy related 9B is a protein that in humans is encoded by the ATG9B gene.^[5]

ATG9B
Identifiers
Aliases	ATG9B, APG9L2, NOS3AS, SONE, autophagy related 9B
External IDs	OMIM: 612205; MGI: 2685420; HomoloGene: 72638; GeneCards: ATG9B; OMA:ATG9B - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q36.1 Start 151,012,209 bp[1] End 151,024,499 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5 A3|5 11.49 cM Start 24,589,179 bp[2] End 24,597,141 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in skin of leg skin of abdomen right testis skin of arm left testis right uterine tube testicle anterior pituitary buccal mucosa cell amniotic fluid Top expressed in lip esophagus skin of back skin of external ear hair follicle lumbar subsegment of spinal cord umbilical cord morula supraoptic nucleus embryo More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 285973 213948 Ensembl ENSG00000181652 ENSMUSG00000038295 UniProt Q674R7 Q6EBV9 RefSeq (mRNA) NM_001317056 NM_001002897 RefSeq (protein) NP_001303985 NP_775952 NP_001002897 Location (UCSC) Chr 7: 151.01 – 151.02 Mb Chr 5: 24.59 – 24.6 Mb PubMed search [3] [4]
Wikidata
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Function

This gene functions in the regulation of autophagy, a lysosomal degradation pathway. This gene also functions as an antisense transcript in the post-transcriptional regulation of the endothelial nitric oxide synthase 3 gene, which has 3' overlap with this gene on the opposite strand. Mutations in this gene and disruption of the autophagy process have been associated with multiple cancers. Alternative splicing results in multiple transcript variants.