Adenosine reuptake inhibitor

An adenosine reuptake inhibitor (AdoRI) is a type of drug which acts as a reuptake inhibitor for the purine nucleoside and neurotransmitter adenosine by blocking the action of one or more of the equilibrative nucleoside transporters (ENTs).^[1][2][3] This in turn leads to increased extracellular concentrations of adenosine and therefore an increase in adenosinergic neurotransmission.

Adenosine

List of AdoRIs

• Acadesine^[4]
• Acetate^[4]
• Barbiturates^[5][6]
• Benzodiazepines^{[5][7][8][9][10][11][12]}
• Calcium channel blockers^[4]
• Carbamazepine^[4]
• Carisoprodol^[13][14][15]
• Cilostazol^[16]
• Cyclobenzaprine^[17][18]
• Dilazep^[1]
• Dipyridamole^[1][19]
• Estradiol^[20]
• Ethanol^[21]
• Flumazenil^[4]
• Hexobendine^[22]
• Hydroxyzine^[23]
• Indomethacin^[4]
• Inosine^[24]
• KF24345^[25]
• Meprobamate^[13][14]
• Nitrobenzylthioguanosine^[26]
• Nitrobenzylthioinosine^[1][27]
• Papaverine^[28]
• Pentoxifylline^[29]
• Phenothiazines^[17][30]
• Phenytoin^[31]
• Progesterone^[20]
• Propentofylline^[32]
• Propofol^[5][33]
• Puromycin^[17]
• R75231^[34]
• RE 102 BS^[35]
• Soluflazine^[36][37]
• Toyocamycin^[17]
• Tracazolate^[23]
• Tricyclic antidepressants^[17][18]

See also

• Adenosinergic
• Reuptake inhibitor