Adp-ribosyltransferase 5

ADP-ribosyltransferase 5 is a protein that in humans is encoded by the ART5 gene. ^[5]

ART5
Identifiers
Aliases	ART5, ARTC5, ADP-ribosyltransferase 5
External IDs	OMIM: 610625; MGI: 107948; HomoloGene: 7231; GeneCards: ART5; OMA:ART5 - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11p15.4 Start 3,638,512 bp[1] End 3,642,316 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7 E2|7 54.71 cM Start 101,746,086 bp[2] End 101,758,696 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in left testis testicle right testis gonad muscle of thigh gastrocnemius muscle left ovary right ovary apex of heart ectocervix Top expressed in spermatid spermatocyte muscle of thigh masseter muscle soleus muscle seminiferous tubule plantaris muscle temporal muscle extensor digitorum longus muscle extraocular muscle More reference expression data BioGPS n/a
Gene ontology Molecular function NAD+ ADP-ribosyltransferase activity NAD+ nucleosidase activity NAD+-protein-arginine ADP-ribosyltransferase activity transferase activity glycosyltransferase activity Cellular component extracellular region membrane Biological process protein ADP-ribosylation peptidyl-arginine ADP-ribosylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 116969 11875 Ensembl ENSG00000167311 ENSMUSG00000070424 UniProt Q96L15 P70352 RefSeq (mRNA) NM_001079536 NM_001297668 NM_053017 NM_001291354 NM_007491 RefSeq (protein) NP_001073004 NP_001284597 NP_443750 NP_001278283 NP_031517 Location (UCSC) Chr 11: 3.64 – 3.64 Mb Chr 7: 101.75 – 101.76 Mb PubMed search [3] [4]
Wikidata
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Function

The protein encoded by this gene belongs to the ARG -specific ADP - ribosyltransferase family. Proteins in this family regulate the function of target proteins by attaching ADP -ribose to specific amino acid residues in their target proteins. The mouse homolog lacks a glycosylphosphatidylinositol-anchor signal sequence and is predicted to be a secretory enzyme. Several transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014].