Anhalonidine

Anhalonidine
Names
	IUPAC name (1S)-1,2,3,4-Tetrahydro-6,7-dimethoxy-1-methyl-8-isoquinolinol
	Other names N-Desmethylpellotine
Identifiers
CAS Number	17627-77-9 ;
3D model (JSmol)	Interactive image;
ChemSpider	78662;
KEGG	C16704 ;
PubChem CID	87201;
UNII	23XP4B16AN ;
CompTox Dashboard (EPA)	DTXSID60876920 ;
	InChI InChI=1S/C12H17NO3/c1-7-10-8(4-5-13-7)6-9(15-2)12(16-3)11(10)14/h6-7,13-14H,4-5H2,1-3H3/t7-/m0/s1 Key: PRNZAMQMBOFSJY-ZETCQYMHSA-N; InChI=1/C12H17NO3/c1-7-10-8(4-5-13-7)6-9(15-2)12(16-3)11(10)14/h6-7,13-14H,4-5H2,1-3H3/t7-/m0/s1 Key: PRNZAMQMBOFSJY-ZETCQYMHBW;
	SMILES C[C@H]1c2c(cc(c(c2O)OC)OC)CCN1;
Properties
Chemical formula	C12H17NO3
Molar mass	223.272 g·mol−1
Melting point	160 °C (320 °F; 433 K)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Anhalonidine, also known as N-desmethylpellotine, a naturally occurring tetrahydroisoquinoline alkaloid which can be isolated from certain members of the cactus family, such as Lophophora.^[2]^[3] It is structurally related to mescaline.^[2] Anhalonidine produced no hallucinogenic effects in humans at doses of up to 250 mg.^[2]^[4] However, it has been reported to have a calming or sedative effect instead, with about one-fourth the potency of pellotine and with marked sedation occurring at doses of 100 to 250 mg.^[2]^[4] Anhalonidine has been found to act as a potent inverse agonist of the serotonin 5-HT₇ receptor.^[5]

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