Auxiliary Activity family 9

Auxiliary Activity family 9 (formerly GH61) is a family of lytic polysaccharide monooxygenases. The family was previously incorrectly classified as glycoside hydrolase family 61, however it was re-classified in March 2013.^[1][2]

Auxiliary Activity Family 9
Identifiers
Symbol	Aux_Act_9
Pfam	PF03443
InterPro	IPR005103
CAZy	AA9
Available protein structures: Pfam   structures / ECOD   PDB RCSB PDB; PDBe; PDBj PDBsum structure summary

AA9 is known to be a copper dependent, oxidative enzyme able to cleave crystalline cellulose.^[3] Activity greatly depends on the presence of a divalent copper ion and a reductant such as gallate or ascorbate. The oxidative action of AA9 can work on either the reducing or the non-reducing end of glucose moieties.^{[citation needed]} Although AA9 enzymes can be found in a large spectrum of biomass degrading fungi, research into this family is relatively new.^[4] This classification is available on the CAZy web site,^[5][6] and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.^[7][8][9]