BCL6B

B-cell CLL/lymphoma 6 member B protein is a protein that in humans is encoded by the BCL6B gene.^[5][6]

BCL6B
Identifiers
Aliases	BCL6B, BAZF, ZBTB28, ZNF62, B-cell CLL/lymphoma 6B, B cell CLL/lymphoma 6B, transcription repressor, BCL6B transcription repressor
External IDs	OMIM: 608992; MGI: 1278332; HomoloGene: 7243; GeneCards: BCL6B; OMA:BCL6B - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17p13.1 Start 7,023,050 bp[1] End 7,030,290 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 B3 Start 70,114,954 bp[2] End 70,120,624 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in upper lobe of left lung apex of heart right lung gonad gallbladder subcutaneous adipose tissue tendon of biceps brachii left ventricle lower lobe of lung left lobe of thyroid gland Top expressed in glomerulus left lung lobe atrium renal vein glomerular capillary aortic valve ascending aorta endocardial cushion vasa recta endothelial cell of lymphatic vessel More reference expression data BioGPS n/a
Gene ontology Molecular function DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific metal ion binding nucleic acid binding DNA-binding transcription factor activity, RNA polymerase II-specific protein binding Cellular component nucleus Biological process negative regulation of transcription by RNA polymerase II type 2 immune response regulation of cell population proliferation regulation of inflammatory response regulation of cell differentiation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 255877 12029 Ensembl ENSG00000161940 ENSMUSG00000000317 UniProt Q8N143 O88282 RefSeq (mRNA) NM_181844 NM_007528 RefSeq (protein) NP_862827 NP_862827.1 NP_031554 Location (UCSC) Chr 17: 7.02 – 7.03 Mb Chr 11: 70.11 – 70.12 Mb PubMed search [3] [4]
Wikidata
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