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BMP2K
Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia
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BMP-2-inducible protein kinase is an enzyme in humans encoded by the BMP2K gene.[5]
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Function
This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene.[5]
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