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BRD9

Mammalian protein found in Homo sapiens From Wikipedia, the free encyclopedia

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Bromodomain-containing protein 9 is a protein that in humans is encoded by the BRD9 gene. [1]

Structure and interaction

BRD9 contains a bromodomain. It is closely related to BRD7. BRD9 is present in some SWI/SNF ATPase remodeling complexes.[2]

Role in cancer

The BRD9 gene is frequently present in variable copy number in lung cancer.[3]

Small molecule inhibition

Small molecules capable of binding to the bromodomain of BRD9 have been developed.[4][5][6]

See also

Bromodomain

References

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