CACUL1

CDK2 associated cullin domain 1 is a protein that in humans is encoded by the CACUL1 gene. ^[5]

CACUL1
Identifiers
Aliases	CACUL1, C10orf46, CAC1, CDK2 associated cullin domain 1
External IDs	MGI: 1926082; HomoloGene: 17821; GeneCards: CACUL1; OMA:CACUL1 - orthologs
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q26.11 Start 118,674,167 bp[1] End 118,755,249 bp[1]
Gene location (Mouse) Chr. Chromosome 19 (mouse)[2] Band 19|19 D3 Start 60,513,134 bp[2] End 60,569,463 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in skin of arm epithelium of nasopharynx cardiac muscle tissue of right atrium amniotic fluid gingival epithelium pancreatic epithelial cell endothelial cell myocardium of left ventricle germinal epithelium parietal pleura Top expressed in spermatid seminiferous tubule tail of embryo arcuate nucleus median eminence extensor digitorum longus muscle cingulate gyrus plantaris muscle stroma of bone marrow paraventricular nucleus of hypothalamus More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding protein kinase binding ubiquitin protein ligase binding ubiquitin protein ligase activity Cellular component cullin-RING ubiquitin ligase complex Biological process cell cycle ubiquitin-dependent protein catabolic process positive regulation of cell population proliferation positive regulation of protein kinase activity G1/S transition of mitotic cell cycle protein ubiquitination Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 143384 78832 Ensembl ENSG00000151893 ENSMUSG00000033417 UniProt Q86Y37 Q8R0X2 RefSeq (mRNA) NM_153810 NM_001172096 NM_001172097 NM_030197 RefSeq (protein) NP_722517 NP_001165567 NP_001165568 NP_084473 Location (UCSC) Chr 10: 118.67 – 118.76 Mb Chr 19: 60.51 – 60.57 Mb PubMed search [3] [4]
Wikidata
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