CALN1

Calcium-binding protein 8 is a protein that in humans is encoded by the CALN1 gene.^[5][6] Alternative splicing results in multiple transcript variants.^[6]

CALN1
Identifiers
Aliases	CALN1, CABP8, calneuron 1
External IDs	OMIM: 607176; MGI: 2155987; HomoloGene: 10966; GeneCards: CALN1; OMA:CALN1 - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q11.22 Start 71,779,491 bp[1] End 72,447,151 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 G1.3- G2 Start 130,398,296 bp[2] End 130,876,253 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in cerebellar vermis pons pars reticulata cerebellar hemisphere pars compacta right hemisphere of cerebellum entorhinal cortex external globus pallidus Brodmann area 46 middle temporal gyrus Top expressed in nucleus accumbens dorsal striatum olfactory tubercle facial motor nucleus deep cerebellar nuclei cerebellar cortex globus pallidus cerebellar vermis lobe of cerebellum temporal lobe More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 83698 140904 Ensembl ENSG00000183166 ENSMUSG00000060371 UniProt Q9BXU9 Q9JJG7 RefSeq (mRNA) NM_001017440 NM_031468 NM_001363460 NM_021371 NM_181045 RefSeq (protein) NP_001017440 NP_113656 NP_001350389 NP_067346 NP_851388 Location (UCSC) Chr 7: 71.78 – 72.45 Mb Chr 5: 130.4 – 130.88 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Function

This gene encodes a protein with high similarity to the calcium-binding proteins of the calmodulin family. The encoded protein contains two EF-hand domains and potential calcium-binding sites.^[7]