CANT1

CANT1 is a gene that encodes soluble calcium-activated nucleotidase 1, an enzyme, in humans.^[5][6]

CANT1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1S18, 1S1D, 2H2N, 2H2U
Identifiers
Aliases	CANT1, DBQD, SCAN-1, SCAN1, SHAPY, DBQD1, calcium activated nucleotidase 1, EDM7
External IDs	OMIM: 613165; MGI: 1923275; HomoloGene: 69460; GeneCards: CANT1; OMA:CANT1 - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q25.3 Start 78,991,716 bp[1] End 79,009,867 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11 E2|11 83.15 cM Start 118,297,115 bp[2] End 118,309,912 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pancreatic ductal cell mucosa of transverse colon rectum mucosa of sigmoid colon mucosa of ileum stromal cell of endometrium blood tibia placenta germinal epithelium Top expressed in pyloric antrum gastrula duodenum intestinal villus spermatocyte large intestine colon epithelium of small intestine crypt of lieberkuhn of small intestine ileum More reference expression data BioGPS More reference expression data
Gene ontology Molecular function uridine-diphosphatase activity hydrolase activity signal transducer activity nucleoside-diphosphatase activity metal ion binding calcium ion binding protein homodimerization activity adenosine-diphosphatase activity guanosine-diphosphatase activity pyrophosphatase activity Cellular component integral component of membrane Golgi cisterna membrane Golgi apparatus extracellular exosome endoplasmic reticulum membrane endoplasmic reticulum extracellular region plasma membrane membrane specific granule lumen tertiary granule lumen ficolin-1-rich granule lumen Biological process positive regulation of I-kappaB kinase/NF-kappaB signaling proteoglycan biosynthetic process signal transduction neutrophil degranulation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 124583 76025 Ensembl ENSG00000171302 ENSMUSG00000025575 UniProt Q8WVQ1 Q8VCF1 RefSeq (mRNA) NM_001159772 NM_001159773 NM_138793 NM_001025617 NM_001025618 NM_001267591 NM_001267592 NM_029502 RefSeq (protein) NP_001153244 NP_001153245 NP_620148 NP_001020788 NP_001020789 NP_001254520 NP_001254521 NP_083778 Location (UCSC) Chr 17: 78.99 – 79.01 Mb Chr 11: 118.3 – 118.31 Mb PubMed search [3] [4]
Wikidata
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