CCDC88A

Girdin is a protein that in humans is encoded by the CCDC88A gene.^[5][6][7] Although its cellular function are not fully elucidated, it has been associated with glioma.^[8]

CCDC88A
Identifiers
Aliases	CCDC88A, APE, GIRDIN, GIV, GRDN, HkRP1, KIAA1212, coiled-coil domain containing 88A, PEHO, PEHOL
External IDs	OMIM: 609736; MGI: 1925177; HomoloGene: 41180; GeneCards: CCDC88A; OMA:CCDC88A - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2p16.1 Start 55,287,842 bp[1] End 55,419,895 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 A3.3 Start 29,323,658 bp[2] End 29,460,808 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in internal globus pallidus corpus callosum ventricular zone ganglionic eminence Achilles tendon subthalamic nucleus buccal mucosa cell inferior ganglion of vagus nerve tendon of biceps brachii testicle Top expressed in Rostral migratory stream barrel cortex tail of embryo genital tubercle lateral septal nucleus lateral geniculate nucleus mammillary body ventromedial nucleus spermatid anterior amygdaloid area More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein homodimerization activity phosphatidylinositol binding actin binding microtubule binding protein kinase B binding dynein light intermediate chain binding G-protein gamma-subunit binding Cellular component cytoplasm Golgi apparatus cell projection endoplasmic reticulum lamellipodium membrane cytoplasmic vesicle cytosol plasma membrane cell leading edge centrosome centriole cytoskeleton ciliary basal body COPI-coated Golgi to ER transport vesicle Biological process regulation of actin cytoskeleton organization nervous system development DNA replication membrane organization cell migration lamellipodium assembly activation of protein kinase B activity regulation of DNA replication TOR signaling regulation of protein phosphorylation regulation of cell population proliferation regulation of neuron projection development cell projection organization cytoskeleton-dependent intracellular transport cytoplasmic microtubule organization positive regulation of cilium assembly positive regulation of protein localization to cilium Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55704 108686 Ensembl ENSG00000115355 ENSMUSG00000032740 UniProt Q3V6T2 Q5SNZ0 RefSeq (mRNA) NM_001135597 NM_001254943 NM_018084 NM_001365480 NM_176841 NM_001363368 NM_001363369 RefSeq (protein) NP_001129069 NP_001241872 NP_060554 NP_001352409 NP_789811 NP_001350297 NP_001350298 Location (UCSC) Chr 2: 55.29 – 55.42 Mb Chr 11: 29.32 – 29.46 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse