Top Qs
Timeline
Chat
Perspective

Integrin alpha 5

Protein From Wikipedia, the free encyclopedia

Integrin alpha 5
Remove ads

Integrin alpha-5 is a protein that in humans is encoded by the ITGA5 gene.[5]

Quick Facts ITGA5, Available structures ...

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.[6]

Remove ads

Interactions

ITGA5 has been shown to interact with GIPC1.[7]

See also

References

Further reading

Loading related searches...

Wikiwand - on

Seamless Wikipedia browsing. On steroids.

Remove ads