Top Qs
Timeline
Chat
Perspective
CDC42EP3
Protein-coding gene in humans From Wikipedia, the free encyclopedia
Remove ads
Cdc42 effector protein 3 is a protein that in humans is encoded by the CDC42EP3 gene.[5][6][7]
CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. This protein can interact with CDC42, as well as with the ras homolog gene family, member Q (ARHQ/TC10). Expression of this protein in fibroblasts has been shown to induce pseudopodia formation.[7]
Remove ads
Interactions
CDC42EP3 has been shown to interact with CDC42[5][8] and RHOQ.[8]
References
External links
Further reading
Wikiwand - on
Seamless Wikipedia browsing. On steroids.
Remove ads