CDH10

Cadherin 10 is a protein that in humans is encoded by the CDH10 gene.^[5][6]

CDH10
Identifiers
Aliases	CDH10, cadherin 10
External IDs	OMIM: 604555; MGI: 107436; HomoloGene: 68530; GeneCards: CDH10; OMA:CDH10 - orthologs
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5p14.2-p14.1 Start 24,487,100 bp[1] End 24,644,978 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15 A2|15 8.2 cM Start 18,819,033 bp[2] End 19,014,322 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Brodmann area 23 middle temporal gyrus Brodmann area 46 orbitofrontal cortex superior frontal gyrus cerebellar hemisphere entorhinal cortex right hemisphere of cerebellum prefrontal cortex dorsolateral prefrontal cortex Top expressed in Subplate barrel cortex prefrontal cortex Region I of hippocampus proper facial motor nucleus ventral tegmental area anterior horn of spinal cord primary motor cortex dorsal tegmental nucleus deep cerebellar nuclei More reference expression data BioGPS n/a
Gene ontology Molecular function calcium ion binding metal ion binding cytoskeletal protein binding protein homodimerization activity cadherin binding Cellular component integral component of membrane plasma membrane membrane glutamatergic synapse GABA-ergic synapse integral component of presynaptic active zone membrane integral component of postsynaptic specialization membrane cell surface catenin complex Biological process cell adhesion adherens junction organization homophilic cell adhesion via plasma membrane adhesion molecules cell-cell adhesion cell-cell junction assembly calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules cell-cell adhesion mediated by cadherin cell morphogenesis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 1008 320873 Ensembl ENSG00000040731 ENSMUSG00000022321 UniProt Q9Y6N8 P70408 RefSeq (mRNA) NM_001190450 NM_006727 NM_001317222 NM_001317224 NM_001362460 NM_009865 NM_001316758 RefSeq (protein) NP_001304151 NP_001304153 NP_006718 NP_001349389 NP_001304153.1 NP_001303687 NP_033995 Location (UCSC) Chr 5: 24.49 – 24.64 Mb Chr 15: 18.82 – 19.01 Mb PubMed search [3] [4]
Wikidata
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Clinical significance

An association with autism has been suggested.^[7]

See also

• Cadherin
• Heritability of autism