CEP164

Centrosomal protein of 164 kDa, also known as CEP164, is a protein that in humans is encoded by the CEP164 gene.^[5][6] Its function appears two be twofold: CEP164 is required for primary cilium formation.^[7] Furthermore, it is an important component in the response to DNA damage by UV light.^[8][9]

CEP164
Identifiers
Aliases	CEP164, NPHP15, centrosomal protein 164
External IDs	OMIM: 614848; MGI: 2384878; HomoloGene: 51110; GeneCards: CEP164; OMA:CEP164 - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q23.3 Start 117,314,557 bp[1] End 117,413,266 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 A5.2 Start 45,678,244 bp[2] End 45,739,989 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sperm tendon of biceps brachii sural nerve nipple right uterine tube bronchial epithelial cell visceral pleura left testis parietal pleura right testis Top expressed in neural layer of retina secondary oocyte Rostral migratory stream internal carotid artery zygote spermatid external carotid artery ureter spermatocyte primary oocyte More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding Cellular component ciliary transition fiber cytoplasm centriole cytosol centrosome cytoskeleton nucleus nucleoplasm extracellular space nuclear speck intracellular membrane-bounded organelle Biological process cell division cell cycle cell projection organization G2/M transition of mitotic cell cycle DNA repair cellular response to DNA damage stimulus cilium assembly ciliary basal body-plasma membrane docking regulation of G2/M transition of mitotic cell cycle Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 22897 214552 Ensembl ENSG00000110274 ENSMUSG00000043987 UniProt Q9UPV0 Q5DU05 RefSeq (mRNA) NM_001271933 NM_014956 NM_001081373 RefSeq (protein) NP_001258862 NP_055771 n/a Location (UCSC) Chr 11: 117.31 – 117.41 Mb Chr 9: 45.68 – 45.74 Mb PubMed search [3] [4]
Wikidata
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