CEP72

Centrosomal protein of 72 kDa is a protein that in humans is encoded by the CEP72 gene.^[5][6]

CEP72
Identifiers
Aliases	CEP72, centrosomal protein 72
External IDs	OMIM: 616475; MGI: 1921720; HomoloGene: 10027; GeneCards: CEP72; OMA:CEP72 - orthologs
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5p15.33 Start 612,340 bp[1] End 667,168 bp[1]
Gene location (Mouse) Chr. Chromosome 13 (mouse)[2] Band 13|13 C1 Start 74,184,619 bp[2] End 74,210,418 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gonad testicle ventricular zone cerebellar hemisphere right hemisphere of cerebellum left testis right testis ganglionic eminence sural nerve right frontal lobe Top expressed in spermatocyte spermatid seminiferous tubule genital tubercle otic vesicle tail of embryo ventricular zone epiblast morula embryo More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding identical protein binding Cellular component cytoplasm microtubule organizing center cytosol centrosome centriolar satellite cytoskeleton Biological process gamma-tubulin complex localization centriole replication spindle organization G2/M transition of mitotic cell cycle regulation of protein localization to centrosome ciliary basal body-plasma membrane docking regulation of G2/M transition of mitotic cell cycle Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55722 74470 Ensembl ENSG00000280688 ENSG00000112877 ENSMUSG00000021572 UniProt Q9P209 Q9D3R3 RefSeq (mRNA) NM_018140 NM_028959 RefSeq (protein) NP_060610 NP_083235 Location (UCSC) Chr 5: 0.61 – 0.67 Mb Chr 13: 74.18 – 74.21 Mb PubMed search [3] [4]
Wikidata
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The product of this gene is a member of the Leucine-rich repeat (LRR) superfamily of proteins. The protein is localized to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells.^[6]