CEP97

Centrosomal protein of 97 kDa (Cep97), also known as leucine-rich repeat and IQ domain-containing protein 2 (LRRIQ2), is a protein that in humans is encoded by the CEP97 gene.^[5]

CEP97
Identifiers
Aliases	CEP97, 2810403B08Rik, LRRIQ2, centrosomal protein 97
External IDs	OMIM: 615864; MGI: 1921451; HomoloGene: 11579; GeneCards: CEP97; OMA:CEP97 - orthologs
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3q12.3 Start 101,724,593 bp[1] End 101,770,562 bp[1]
Gene location (Mouse) Chr. Chromosome 16 (mouse)[2] Band 16|16 C1.1 Start 55,720,251 bp[2] End 55,755,218 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in corpus callosum endothelial cell mucosa of paranasal sinus inferior ganglion of vagus nerve oocyte internal globus pallidus secondary oocyte superior vestibular nucleus subthalamic nucleus ventricular zone Top expressed in Rostral migratory stream hand otolith organ utricle thymus cumulus cell blood pineal gland ciliary body spermatocyte More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding calmodulin binding Cellular component centrosome cytoskeleton microtubule organizing center cytoplasm cytosol protein-containing complex Biological process cell projection organization negative regulation of cilium assembly regulation of mitotic spindle assembly ciliary basal body-plasma membrane docking Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79598 74201 Ensembl ENSG00000182504 ENSMUSG00000022604 UniProt Q8IW35 Q9CZ62 RefSeq (mRNA) NM_001303401 NM_024548 NM_001159364 NM_001159365 NM_001159366 NM_028815 RefSeq (protein) NP_001290330 NP_078824 NP_001152836 NP_001152837 NP_001152838 NP_083091 Location (UCSC) Chr 3: 101.72 – 101.77 Mb Chr 16: 55.72 – 55.76 Mb PubMed search [3] [4]
Wikidata
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Cep97 along with CP110 inhibit generation of cilia.^[6]