CFHR1

Complement factor H-related protein 1 is a protein that in humans is encoded by the CFHR1 gene.^[5][6][7]

CFHR1
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 3ZD2, 4MUC
Identifiers
Aliases	CFHR1, CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, H36-1, H36-2, HFL1, HFL2, complement factor H related 1
External IDs	OMIM: 134371; MGI: 2138169; HomoloGene: 55632; GeneCards: CFHR1; OMA:CFHR1 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q31.3 Start 196,819,757 bp[1] End 196,832,189 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 F Start 139,474,791 bp[2] End 139,488,010 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of liver testicle lymph node gonad spleen tibial nerve human kidney stromal cell of endometrium appendix right hemisphere of cerebellum Top expressed in left lobe of liver gallbladder cardiac muscle tissue of left ventricle interventricular septum extraocular muscle CA3 field perirhinal cortex entorhinal cortex lactiferous gland sciatic nerve More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding protein homodimerization activity protein heterodimerization activity Cellular component extracellular exosome blood microparticle extracellular space extracellular region protein-containing complex Biological process complement activation regulation of complement activation negative regulation of protein binding positive regulation of cytolysis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3078 50702 Ensembl ENSG00000244414 ENSMUSG00000057037 UniProt Q03591 n/a RefSeq (mRNA) NM_002113 NM_015780 RefSeq (protein) NP_002104 NP_001366235 NP_001366236 NP_001366237 NP_001366238 NP_001366239 NP_001366240 NP_001366241 n/a Location (UCSC) Chr 1: 196.82 – 196.83 Mb Chr 1: 139.47 – 139.49 Mb PubMed search [3] [4]
Wikidata
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