CHMP4A

Charged multivesicular body protein 4a is a protein that in humans is encoded by the CHMP4A gene.^[3]

CHMP4A
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 3C3O
Identifiers
Aliases	CHMP4A, C14orf123, CHMP4, CHMP4B, HSPC134, SHAX2, SNF7, SNF7-1, VPS32-1, VPS32A, charged multivesicular body protein 4A
External IDs	OMIM: 610051; HomoloGene: 69160; GeneCards: CHMP4A; OMA:CHMP4A - orthologs
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q12 Start 24,209,615 bp[1] End 24,213,830 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in popliteal artery tibial arteries substantia nigra granulocyte monocyte muscle layer of sigmoid colon C1 segment mucosa of transverse colon left coronary artery amygdala n/a More reference expression data BioGPS n/a
Gene ontology Molecular function protein homodimerization activity ATPase binding protein binding identical protein binding lipid binding Cellular component cytoplasm ESCRT III complex cytosol endosome membrane late endosome membrane plasma membrane midbody cytoplasmic side of plasma membrane membrane coat cytoplasmic vesicle membrane cytoplasmic vesicle nucleus Biological process negative regulation of autophagosome assembly protein polymerization viral life cycle nucleus organization membrane invagination multivesicular body assembly plasma membrane tubulation endosomal transport posttranslational protein targeting to endoplasmic reticulum membrane vesicle budding from membrane protein transport septum digestion after cytokinesis mitotic metaphase plate congression protein homooligomerization vacuolar transport negative regulation of neuron death macroautophagy viral budding via host ESCRT complex midbody abscission Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 29082 n/a Ensembl ENSG00000254505 ENSG00000285302 n/a UniProt Q9BY43 n/a RefSeq (mRNA) NM_014169 n/a RefSeq (protein) NP_054888 n/a Location (UCSC) Chr 14: 24.21 – 24.21 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human