CHRNB4

Neuronal acetylcholine receptor subunit beta-4 is a protein that in humans is encoded by the CHRNB4 gene.^[5][6]

CHRNB4
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2ASG
Identifiers
Aliases	CHRNB4, cholinergic receptor nicotinic beta 4 subunit
External IDs	OMIM: 118509; MGI: 87892; HomoloGene: 20196; GeneCards: CHRNB4; OMA:CHRNB4 - orthologs
Gene location (Human) Chr. Chromosome 15 (human)[1] Band 15q25.1 Start 78,624,111 bp[1] End 78,727,754 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 B Start 54,935,438 bp[2] End 54,956,063 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gonad testicle right testis left testis ganglionic eminence muscle layer of sigmoid colon ventricular zone sural nerve right adrenal gland appendix Top expressed in habenula lumbar spinal ganglion pineal gland ciliary body pretectal area iris Paneth cell embryo adrenal gland carotid body More reference expression data BioGPS More reference expression data
Gene ontology Molecular function acetylcholine binding acetylcholine receptor activity ion channel activity ligand-gated ion channel activity protein heterodimerization activity extracellular ligand-gated ion channel activity protein binding acetylcholine-gated cation-selective channel activity transmembrane signaling receptor activity transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component acetylcholine-gated channel complex integral component of membrane postsynaptic membrane membrane plasma membrane synapse integral component of plasma membrane cell junction neuron projection specific granule membrane tertiary granule membrane cholinergic synapse Biological process smooth muscle contraction locomotory behavior regulation of smooth muscle contraction protein heterooligomerization positive regulation of transmission of nerve impulse regulation of membrane potential response to nicotine synaptic transmission, cholinergic ion transport regulation of neurotransmitter secretion behavioral response to nicotine synaptic transmission involved in micturition action potential signal transduction neutrophil degranulation regulation of postsynaptic membrane potential excitatory postsynaptic potential ion transmembrane transport chemical synaptic transmission neuromuscular synaptic transmission nervous system process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 1143 108015 Ensembl ENSG00000117971 ENSMUSG00000035200 UniProt P30926 Q8R493 RefSeq (mRNA) NM_000750 NM_001256567 NM_148944 RefSeq (protein) NP_000741 NP_001243496 NP_683746 Location (UCSC) Chr 15: 78.62 – 78.73 Mb Chr 9: 54.94 – 54.96 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Interactive pathway map

Click on genes, proteins and metabolites below to link to respective Wikipedia articles. ^{[§ 1]}

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|alt=Nicotine Activity on Chromaffin Cells edit]]

Nicotine Activity on Chromaffin Cells edit

1. The interactive pathway map can be edited at WikiPathways: "NicotineActivityonChromaffinCells_WP1603".

See also

• Nicotinic acetylcholine receptor