CHST10

Carbohydrate sulfotransferase 10 is an enzyme that in humans is encoded by the CHST10 gene.^[5][6]

CHST10
Identifiers
Aliases	CHST10, HNK-1ST, HNK1ST, carbohydrate sulfotransferase 10
External IDs	OMIM: 606376; MGI: 2138283; HomoloGene: 21013; GeneCards: CHST10; OMA:CHST10 - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q11.2 Start 100,391,860 bp[1] End 100,417,668 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 B Start 38,902,948 bp[2] End 38,937,242 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ventricular zone ganglionic eminence lateral nuclear group of thalamus middle temporal gyrus frontal pole Brodmann area 10 right frontal lobe Brodmann area 9 secondary oocyte putamen Top expressed in lumbar subsegment of spinal cord visual cortex superior frontal gyrus dentate gyrus of hippocampal formation granule cell primary visual cortex central gray substance of midbrain cerebellar cortex medial dorsal nucleus dorsal tegmental nucleus nucleus of stria terminalis More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transferase activity sulfotransferase activity HNK-1 sulfotransferase activity Cellular component integral component of membrane Golgi membrane Golgi apparatus membrane Biological process cell adhesion carbohydrate biosynthetic process carbohydrate metabolic process proteoglycan biosynthetic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9486 98388 Ensembl ENSG00000115526 ENSMUSG00000026080 UniProt O43529 Q6PGK7 RefSeq (mRNA) NM_004854 NM_145142 NM_001368780 RefSeq (protein) NP_004845 NP_660124 NP_001355709 Location (UCSC) Chr 2: 100.39 – 100.42 Mb Chr 1: 38.9 – 38.94 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Cell surface carbohydrates modulate a variety of cellular functions and are typically synthesized in a stepwise manner. HNK1ST plays a role in the biosynthesis of HNK1 (see MIM 151290), a neuronally expressed carbohydrate that contains a sulfoglucuronyl residue.[supplied by OMIM]^[6]