CIAPIN1

Anamorsin is a protein that in humans is encoded by the CIAPIN1 gene.^[5][6][7]

CIAPIN1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2LD4, 2YUI, 4M7R
Identifiers
Aliases	CIAPIN1, 2810413N20Rik, Anamorsin, DRE2, PRO0915, cytokine induced apoptosis inhibitor 1, CIAE2
External IDs	OMIM: 608943; MGI: 1922083; HomoloGene: 10658; GeneCards: CIAPIN1; OMA:CIAPIN1 - orthologs
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16q21 Start 57,428,187 bp[1] End 57,447,420 bp[1]
Gene location (Mouse) Chr. Chromosome 8 (mouse)[2] Band 8|8 C5 Start 95,546,432 bp[2] End 95,564,986 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in oocyte secondary oocyte left testis right testis sperm mucosa of transverse colon right adrenal cortex embryo apex of heart ganglionic eminence Top expressed in otic placode saccule spermatocyte spermatid yolk sac primitive streak facial motor nucleus fetal liver hematopoietic progenitor cell neural tube embryo More reference expression data BioGPS n/a
Gene ontology Molecular function methyltransferase activity iron-sulfur cluster binding protein binding metal ion binding 2 iron, 2 sulfur cluster binding 4 iron, 4 sulfur cluster binding electron transfer activity Cellular component cytoplasm mitochondrial intermembrane space nucleolus nucleus nucleoplasm mitochondrion Biological process methylation metabolism negative regulation of apoptotic process iron-sulfur cluster assembly apoptotic process hemopoiesis electron transport chain Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 57019 109006 Ensembl ENSG00000005194 ENSMUSG00000031781 UniProt Q6FI81 Q8WTY4 RefSeq (mRNA) NM_001308347 NM_001308358 NM_020313 NM_134141 RefSeq (protein) NP_001295276 NP_001295287 NP_064709 NP_598902 Location (UCSC) Chr 16: 57.43 – 57.45 Mb Chr 8: 95.55 – 95.56 Mb PubMed search [3] [4]
Wikidata
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CIAPIN1 is a cytokine-induced inhibitor of apoptosis with no relation to apoptosis regulatory molecules of the BCL2 (MIM 151430) or CASP (see MIM 147678) families. Expression of CIAPIN1 is dependent on growth factor stimulation (Shibayama et al., 2004).[supplied by OMIM]^[7]