CITED1

Cbp/p300-interacting transactivator 1 is a protein that in humans is encoded by the CITED1 gene.^[5][6][7]

CITED1
Identifiers
Aliases	CITED1, MSG1, Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1
External IDs	OMIM: 300149; MGI: 108023; HomoloGene: 3057; GeneCards: CITED1; OMA:CITED1 - orthologs
Gene location (Human) Chr. X chromosome (human)[1] Band Xq13.1 Start 72,301,638 bp[1] End 72,307,187 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X D|X 45.25 cM Start 101,290,987 bp[2] End 101,295,787 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right testis left testis anterior pituitary hypothalamus testicle prefrontal cortex anterior cingulate cortex amygdala dorsolateral prefrontal cortex superior frontal gyrus Top expressed in yolk sac morula tail of embryo reticular formation atrium paraxial mesoderm lactiferous gland raphe nuclei endocardium endocardial cushion More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transcription coactivator activity co-SMAD binding protein homodimerization activity DNA-binding transcription factor activity chromatin binding LBD domain binding protein C-terminus binding protein binding Cellular component cytoplasm cytosol nucleus nucleoplasm Biological process negative regulation of neuron apoptotic process response to transforming growth factor beta positive regulation of transforming growth factor beta receptor signaling pathway cell differentiation response to cytokine melanin biosynthetic process spongiotrophoblast layer development response to interleukin-1 regulation of transcription, DNA-templated SMAD protein signal transduction response to interleukin-4 response to interferon-gamma response to interleukin-6 placenta development regulation of transcription by RNA polymerase II response to interleukin-2 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis labyrinthine layer development response to interleukin-11 negative regulation of Wnt signaling pathway embryonic axis specification negative regulation of osteoblast differentiation transcription, DNA-templated response to estrogen vasculogenesis positive regulation of transcription, DNA-templated response to insulin multicellular organism development response to lipopolysaccharide branching involved in ureteric bud morphogenesis brain development positive regulation of gene expression response to parathyroid hormone nucleocytoplasmic transport pigmentation response to cAMP cell population proliferation metanephros development melanocyte differentiation negative regulation of transcription, DNA-templated response to interleukin-9 transforming growth factor beta receptor signaling pathway mesenchymal to epithelial transition apoptotic process positive regulation of transcription by RNA polymerase II regulation of apoptotic process transcription by RNA polymerase II positive regulation of mesenchymal stem cell proliferation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 4435 12705 Ensembl ENSG00000125931 ENSMUSG00000051159 UniProt Q99966 P97769 RefSeq (mRNA) NM_001144885 NM_001144886 NM_001144887 NM_004143 NM_001276466 NM_001276473 NM_001276474 NM_007709 RefSeq (protein) NP_001138357 NP_001138358 NP_001138359 NP_004134 NP_001263395 NP_001263402 NP_001263403 NP_031735 Location (UCSC) Chr X: 72.3 – 72.31 Mb Chr X: 101.29 – 101.3 Mb PubMed search [3] [4]
Wikidata
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Interactions

CITED1 has been shown to interact with HSPA8^[8] and EP300.^[8]