CLDN12

Claudin-12 is a protein that in humans is encoded by the CLDN12 gene.^[5] It belongs to the group of claudins.

CLDN12
Identifiers
Aliases	CLDN12, claudin 12
External IDs	OMIM: 611232; MGI: 1929288; HomoloGene: 40809; GeneCards: CLDN12; OMA:CLDN12 - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q21.13 Start 90,383,721 bp[1] End 90,513,402 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 A1 Start 5,539,537 bp[2] End 5,564,958 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte islet of Langerhans pancreatic epithelial cell cartilage tissue mucosa of sigmoid colon right lobe of liver rectum pituitary gland anterior pituitary myocardium of left ventricle Top expressed in otolith organ utricle interventricular septum retinal pigment epithelium ascending aorta supraoptic nucleus ciliary body primitive streak aortic valve epithelium of lens More reference expression data BioGPS n/a
Gene ontology Molecular function structural molecule activity identical protein binding protein binding Cellular component integral component of membrane cell junction lateral plasma membrane membrane cell periphery bicellular tight junction plasma membrane Biological process calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9069 64945 Ensembl ENSG00000157224 ENSMUSG00000046798 UniProt P56749 Q9ET43 RefSeq (mRNA) NM_012129 NM_001185072 NM_001185073 NM_001193659 NM_001193660 NM_001193661 NM_022890 RefSeq (protein) NP_001172001 NP_001172002 NP_036261 NP_001180588 NP_001180589 NP_001180590 NP_075028 Location (UCSC) Chr 7: 90.38 – 90.51 Mb Chr 5: 5.54 – 5.56 Mb PubMed search [3] [4]
Wikidata
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