CLDN6

Claudin-6 is a protein that in humans is encoded by the CLDN6 gene.^[5][6][7] It belongs to the group of claudins. The knockout mice of mouse homolog exhibit no phenotype, indicating that claudin-6 is dispensable for normal development and homeostasis.

CLDN6
Identifiers
Aliases	CLDN6, claudin 6
External IDs	OMIM: 615798; MGI: 1859284; HomoloGene: 10300; GeneCards: CLDN6; OMA:CLDN6 - orthologs
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16p13.3 Start 3,014,712 bp[1] End 3,020,071 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17|17 A3.3 Start 23,898,223 bp[2] End 23,901,420 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gonad islet of Langerhans putamen placenta cerebellar hemisphere striated muscle tissue skeletal muscle tissue right hemisphere of cerebellum stromal cell of endometrium metanephros Top expressed in yolk sac embryo epiblast genital tubercle tail of embryo primitive streak blastocyst glomerulus morula renal vein More reference expression data BioGPS More reference expression data
Gene ontology Molecular function structural molecule activity identical protein binding protein binding virus receptor activity Cellular component bicellular tight junction cell junction membrane apicolateral plasma membrane integral component of membrane plasma membrane Biological process cell-cell junction organization viral process calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules viral entry into host cell Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9074 54419 Ensembl ENSG00000184697 ENSMUSG00000023906 UniProt P56747 Q9Z262 RefSeq (mRNA) NM_021195 NM_018777 RefSeq (protein) NP_067018 NP_061247 Location (UCSC) Chr 16: 3.01 – 3.02 Mb Chr 17: 23.9 – 23.9 Mb PubMed search [3] [4]
Wikidata
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