CLEC11A

C-type lectin domain family 11 member A is a protein that in humans is encoded by the CLEC11A gene.^[5][6][7]

CLEC11A
Identifiers
Aliases	CLEC11A, CLECSF3, LSLCL, P47, SCGF, C-type lectin domain family 11 member A, C-type lectin domain containing 11A
External IDs	OMIM: 604713; MGI: 1298219; HomoloGene: 2236; GeneCards: CLEC11A; OMA:CLEC11A - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19q13.33 Start 50,723,364 bp[1] End 50,725,708 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 B3 Start 43,952,111 bp[2] End 43,956,326 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in stromal cell of endometrium tibia periodontal fiber trabecular bone canal of the cervix bone marrow right ovary left uterine tube left ovary right uterine tube Top expressed in calvaria body of femur fossa condyle umbilical cord molar ankle vestibular sensory epithelium ascending aorta carotid body More reference expression data BioGPS More reference expression data
Gene ontology Molecular function growth factor activity carbohydrate binding Cellular component cytoplasm extracellular region extracellular space Biological process positive regulation of cell population proliferation ossification regulation of signaling receptor activity signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6320 20256 Ensembl ENSG00000105472 ENSMUSG00000004473 UniProt Q9Y240 O88200 RefSeq (mRNA) NM_002975 NM_009131 RefSeq (protein) NP_002966 NP_033157 Location (UCSC) Chr 19: 50.72 – 50.73 Mb Chr 7: 43.95 – 43.96 Mb PubMed search [3] [4]
Wikidata
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Function

This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined.^[7]