CLEC1A

C-type lectin domain family 1 member A is a protein that in humans is encoded by the CLEC1A gene.^[5][6][7]

CLEC1A
Identifiers
Aliases	CLEC1A, CLEC-1, CLEC1, C-type lectin domain family 1 member A
External IDs	OMIM: 606782; MGI: 2444151; HomoloGene: 9549; GeneCards: CLEC1A; OMA:CLEC1A - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12p13.2 Start 10,069,554 bp[1] End 10,111,627 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 F3 Start 129,401,735 bp[2] End 129,428,963 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in placenta upper lobe of left lung right lung subcutaneous adipose tissue testicle tibial nerve body of uterus canal of the cervix ectocervix left uterine tube Top expressed in left lung lobe right lung lumbar spinal ganglion right lung lobe renal corpuscle carotid body mesenteric lymph nodes sciatic nerve atrioventricular valve cumulus cell More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transmembrane signaling receptor activity carbohydrate binding Cellular component integral component of membrane integral component of plasma membrane intracellular anatomical structure membrane Biological process cell surface receptor signaling pathway defense response Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51267 243653 Ensembl ENSG00000150048 ENSMUSG00000033082 UniProt Q8NC01 Q8BWY2 RefSeq (mRNA) NM_001297748 NM_001297749 NM_001297750 NM_001297751 NM_016511 NM_175526 NM_001347475 RefSeq (protein) NP_001284677 NP_001284678 NP_001284679 NP_001284680 NP_057595 NP_001284677.1 NP_001334404 NP_780735 Location (UCSC) Chr 12: 10.07 – 10.11 Mb Chr 6: 129.4 – 129.43 Mb PubMed search [3] [4]
Wikidata
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This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded protein may play a role in regulating dendritic cell function. Alternative splice variants have been described but their biological nature has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.^[7]