CMLD-2

CMLD-2 is an experimental drug which acts as an inhibitor of the RNA-binding HuR protein. Elevated levels of HuR are found in many forms of cancer, and CMLD-2 is being researched for potential applications in cancer treatment.^[1][2][3][4] It also has anti-inflammatory effects, and may also be useful for the treatment of neuropathic pain,^[5][6] as well as asthma,^[7] and Hepatitis B.^[8]

CMLD-2

Identifiers
IUPAC name 5,7-dimethoxy-8-[1-(4-methoxyphenyl)-3-oxo-3-pyrrolidin-1-ylpropyl]-4-phenylchromen-2-one
CAS Number	958843-91-9
PubChem CID	16746438
ChemSpider	20577668
ChEMBL	ChEMBL1499653
Chemical and physical data
Formula	C31H31NO6
Molar mass	513.590 g·mol−1
3D model (JSmol)	Interactive image
SMILES COC1=CC=C(C=C1)C(CC(=O)N2CCCC2)C3=C(C=C(C4=C3OC(=O)C=C4C5=CC=CC=C5)OC)OC
InChI InChI=1S/C31H31NO6/c1-35-22-13-11-21(12-14-22)23(17-27(33)32-15-7-8-16-32)29-25(36-2)19-26(37-3)30-24(18-28(34)38-31(29)30)20-9-5-4-6-10-20/h4-6,9-14,18-19,23H,7-8,15-17H2,1-3H3 Key:PROGRNRRJJYCNX-UHFFFAOYSA-N

See also

• KH-3
• SRI-42127