CNTROB

Centrobin is a protein that in humans is encoded by the CNTROB gene.^[5] It is a centriole-associated protein that asymmetrically localizes to the daughter centriole, and is required for centriole duplication and cytokinesis.^[6]

CNTROB
Identifiers
Aliases	CNTROB, LIP8, PP1221, centrobin, centriole duplication and spindle assembly protein
External IDs	OMIM: 611425; MGI: 2443290; HomoloGene: 14205; GeneCards: CNTROB; OMA:CNTROB - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17p13.1 Start 7,932,101 bp[1] End 7,949,920 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 B3 Start 69,299,487 bp[2] End 69,323,775 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in left testis right testis ventricular zone body of uterus ganglionic eminence right lung upper lobe of left lung pancreatic ductal cell canal of the cervix cardiac muscle tissue of right atrium Top expressed in superior surface of tongue gallbladder ventricular zone otic vesicle neural layer of retina secondary oocyte spermatocyte zygote thymus primary oocyte More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding protein domain specific binding Cellular component centriole centrosome cytoskeleton cytoplasm cytosol Biological process cell cycle mitotic cytokinetic process centrosome separation cell division centriole replication regulation of cilium assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 116840 216846 Ensembl ENSG00000170037 ENSMUSG00000032782 UniProt Q8N137 Q8CB62 RefSeq (mRNA) NM_001037144 NM_053051 NM_001330124 NM_001353202 NM_001353203 NM_001353204 NM_001353205 NM_001353206 NM_001353207 NM_001353208 NM_001353209 NM_172560 RefSeq (protein) NP_001032221 NP_001317053 NP_444279 NP_001340131 NP_001340132 NP_001340133 NP_001340134 NP_001340135 NP_001340136 NP_001340137 NP_001340138 NP_766148 Location (UCSC) Chr 17: 7.93 – 7.95 Mb Chr 11: 69.3 – 69.32 Mb PubMed search [3] [4]
Wikidata
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