COPG

Coatomer subunit gamma is a protein that in humans is encoded by the COPG gene.^[5][6] It is one of seven proteins in the COPI coatomer complex that coats vesicles as they bud from the Golgi complex.^[5]

COPG1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1R4X
Identifiers
Aliases	COPG1, COPG, coatomer protein complex subunit gamma 1, COPI coat complex subunit gamma 1
External IDs	OMIM: 615525; MGI: 1858696; HomoloGene: 56745; GeneCards: COPG1; OMA:COPG1 - orthologs
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3q21.3 Start 129,249,606 bp[1] End 129,277,773 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6 D1|6 39.13 cM Start 87,864,796 bp[2] End 87,890,577 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in stromal cell of endometrium anterior pituitary body of pancreas mucosa of transverse colon islet of Langerhans minor salivary glands right lobe of thyroid gland body of stomach right adrenal gland rectum Top expressed in yolk sac dentate gyrus of hippocampal formation granule cell molar superior frontal gyrus supraoptic nucleus pituitary gland dermis central gray substance of midbrain islet of Langerhans crypt of lieberkuhn of small intestine More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding structural molecule activity Cellular component cytoplasm membrane coat COPI-coated vesicle membrane membrane transport vesicle cytosol cytoplasmic vesicle Golgi apparatus Golgi membrane COPI vesicle coat endoplasmic reticulum membrane endoplasmic reticulum endoplasmic reticulum-Golgi intermediate compartment Biological process retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum protein transport organelle transport along microtubule intracellular protein transport establishment of Golgi localization endoplasmic reticulum to Golgi vesicle-mediated transport vesicle-mediated transport intra-Golgi vesicle-mediated transport protein secretion Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 22820 54161 Ensembl ENSG00000181789 ENSMUSG00000030058 UniProt Q9Y678 Q9QZE5 RefSeq (mRNA) NM_016128 NM_017477 NM_201244 RefSeq (protein) NP_057212 NP_059505 NP_957696 Location (UCSC) Chr 3: 129.25 – 129.28 Mb Chr 6: 87.86 – 87.89 Mb PubMed search [3] [4]
Wikidata
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Interactions

COPG has been shown to interact with Dopamine receptor D1,^[7] COPZ1^[5][8] and COPB1.^[5][9]