COPS7A

COP9 signalosome complex subunit 7a is a protein that in humans is encoded by the COPS7A gene.^[5]

COPS7A
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4D10, 4D18, 4WSN
Identifiers
Aliases	COPS7A, CSN7A, SGN7a, CSN7, COP9 signalosome subunit 7A
External IDs	OMIM: 616009; MGI: 1349400; HomoloGene: 22685; GeneCards: COPS7A; OMA:COPS7A - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12p13.31 Start 6,724,014 bp[1] End 6,731,875 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6 F2|6 59.17 cM Start 124,935,376 bp[2] End 124,942,501 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in prefrontal cortex stromal cell of endometrium right frontal lobe cingulate gyrus anterior cingulate cortex Brodmann area 9 apex of heart right adrenal gland right adrenal cortex gastrocnemius muscle Top expressed in spermatocyte spermatid muscle of thigh tail of embryo genital tubercle yolk sac dentate gyrus of hippocampal formation granule cell superior frontal gyrus lip blastocyst More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component COP9 signalosome nucleus nucleoplasm cytoplasm cytosol Biological process transcription-coupled nucleotide-excision repair nucleotide-excision repair, DNA damage recognition protein deneddylation post-translational protein modification viral process COP9 signalosome assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 50813 26894 Ensembl ENSG00000111652 ENSMUSG00000030127 UniProt Q9UBW8 Q9CZ04 RefSeq (mRNA) NM_001164093 NM_001164094 NM_001164095 NM_016319 NM_001164089 NM_012003 NM_001355541 NM_001355542 NM_001379119 NM_001379120 NM_001379122 NM_001379123 NM_001379124 NM_001379125 RefSeq (protein) NP_001157565 NP_001157566 NP_001157567 NP_057403 NP_001157561 NP_036133 NP_001342470 NP_001342471 NP_001366048 NP_001366049 NP_001366051 NP_001366052 NP_001366053 NP_001366054 Location (UCSC) Chr 12: 6.72 – 6.73 Mb Chr 6: 124.94 – 124.94 Mb PubMed search [3] [4]
Wikidata
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