CPNE8

Copine-8 is a protein that in humans is encoded by the CPNE8 gene.^[5][6]

CPNE8
Identifiers
Aliases	CPNE8, copine 8
External IDs	MGI: 1914121; HomoloGene: 12049; GeneCards: CPNE8; OMA:CPNE8 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q12 Start 38,646,822 bp[1] End 38,907,430 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15|15 E3 Start 90,371,685 bp[2] End 90,563,635 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pancreatic epithelial cell Achilles tendon sperm monocyte right auricle of heart testicle right lung retinal pigment epithelium subcutaneous adipose tissue right lobe of liver Top expressed in lumbar spinal ganglion lateral septal nucleus epithelium of small intestine seminal vesicula lip Region I of hippocampus proper otolith organ utricle facial motor nucleus blastocyst More reference expression data BioGPS n/a
Gene ontology Molecular function molecular function calcium-dependent phospholipid binding Cellular component extracellular exosome plasma membrane Biological process biological process cellular response to calcium ion Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 144402 66871 Ensembl ENSG00000139117 ENSMUSG00000052560 UniProt Q86YQ8 Q9DC53 RefSeq (mRNA) NM_153634 NM_001033851 NM_025815 NM_001357979 RefSeq (protein) NP_705898 NP_001029023 NP_080091 NP_001344908 Location (UCSC) Chr 12: 38.65 – 38.91 Mb Chr 15: 90.37 – 90.56 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus.^[6]