CRIP2

Cysteine-rich protein 2 is a protein that in humans is encoded by the CRIP2 gene.^[5][6][7][8]

CRIP2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2CU8
Identifiers
Aliases	CRIP2, CRIP, CRP2, ESP1, cysteine rich protein 2
External IDs	OMIM: 601183; MGI: 1915587; HomoloGene: 135666; GeneCards: CRIP2; OMA:CRIP2 - orthologs
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q32.33 Start 105,472,962 bp[1] End 105,480,162 bp[1]
Gene location (Mouse) Chr. Chromosome 12 (mouse)[2] Band 12 F1|12 61.57 cM Start 113,103,856 bp[2] End 113,109,126 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in apex of heart right auricle of heart right coronary artery popliteal artery tibial arteries Descending thoracic aorta ascending aorta left coronary artery right uterine tube left ventricle Top expressed in ankle joint right ventricle right lung right lung lobe left lung gastrula interventricular septum endothelial cell of lymphatic vessel lip atrium More reference expression data BioGPS More reference expression data
Gene ontology Molecular function metal ion binding zinc ion binding protein binding Cellular component cell cortex Biological process positive regulation of cell population proliferation hemopoiesis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 1397 68337 Ensembl ENSG00000182809 ENSMUSG00000006356 UniProt P52943 Q9DCT8 RefSeq (mRNA) NM_001270837 NM_001270841 NM_001312 NM_024223 NM_001347443 RefSeq (protein) NP_001257766 NP_001257770 NP_001303 NP_001334372 NP_077185 Location (UCSC) Chr 14: 105.47 – 105.48 Mb Chr 12: 113.1 – 113.11 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

CRIP2 and the closely related CRIP1 are cysteine-rich proteins containing two LIM domains. They are highly expressed during cardiovascular development and act to bridge serum response factor and GATA proteins and stimulate smooth muscle target genes.^[9]