CSRP2

Cysteine and glycine-rich protein 2 is a protein that in humans is encoded by the CSRP2 gene.^[5][6][7]

CSRP2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2CU8
Identifiers
Aliases	CSRP2, CRP2, LMO5, SmLIM, cysteine and glycine rich protein 2
External IDs	OMIM: 601871; MGI: 1202907; HomoloGene: 111061; GeneCards: CSRP2; OMA:CSRP2 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q21.2 Start 76,858,709 bp[1] End 76,879,023 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 D1 Start 110,755,650 bp[2] End 110,775,483 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in oocyte secondary oocyte ganglionic eminence tibial arteries right coronary artery mucosa of paranasal sinus parietal pleura gingival epithelium gastric mucosa optic nerve Top expressed in ascending aorta aortic valve tunica media of zone of aorta umbilical cord endocardial cushion atrium mandibular prominence external carotid artery atrioventricular valve internal carotid artery More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding metal ion binding molecular function structural constituent of muscle actinin binding Cellular component nucleus focal adhesion cytoplasm Z discdkac Biological process multicellular organism development cell differentiation actin cytoskeleton organization sarcomere organization muscle tissue development Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 1466 13008 Ensembl ENSG00000175183 ENSMUSG00000020186 UniProt Q16527 P97314 RefSeq (mRNA) NM_001300965 NM_001321 NM_007792 RefSeq (protein) NP_001287894 NP_001312 NP_031818 Location (UCSC) Chr 12: 76.86 – 76.88 Mb Chr 10: 110.76 – 110.78 Mb PubMed search [3] [4]
Wikidata
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CSRP2 is a member of the CSRP family of genes, encoding a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. CRP2 contains two copies of the cysteine-rich amino acid sequence motif (LIM) with putative zinc-binding activity, and may be involved in regulating ordered cell growth. Other genes in the family include CSRP1 and CSRP3.^[7]