CSRP2BP

CSRP2 binding protein is a protein that in humans is encoded by the CSRP2BP gene.^[5]

KAT14
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2CU8
Identifiers
Aliases	KAT14, ATAC2, CRP2BP, PRO1194, dJ717M23.1, CSRP2BP, lysine acetyltransferase 14
External IDs	OMIM: 617501; MGI: 1917264; HomoloGene: 10745; GeneCards: KAT14; OMA:KAT14 - orthologs
Gene location (Human) Chr. Chromosome 20 (human)[1] Band 20p11.23 Start 18,138,118 bp[1] End 18,188,387 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2 G1|2 71.01 cM Start 144,210,903 bp[2] End 144,249,596 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in deltoid muscle quadriceps femoris muscle vastus lateralis muscle skin of arm cardiac muscle tissue of right atrium gonad myocardium of left ventricle Skeletal muscle tissue of biceps brachii tibialis anterior muscle testicle Top expressed in primary oocyte zygote internal carotid artery external carotid artery secondary oocyte genital tubercle hand otolith organ utricle tail of embryo More reference expression data BioGPS n/a
Gene ontology Molecular function LIM domain binding protein binding histone acetyltransferase activity Cellular component cytoplasm nucleus Biological process G2/M transition of mitotic cell cycle histone acetylation histone H3 acetylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 57325 228714 Ensembl ENSG00000149474 ENSMUSG00000027425 UniProt Q9H8E8 Q8CID0 RefSeq (mRNA) NM_020536 NM_177926 NM_001166640 NM_181417 RefSeq (protein) NP_065397 NP_001371121 NP_001160112 NP_852082 Location (UCSC) Chr 20: 18.14 – 18.19 Mb Chr 2: 144.21 – 144.25 Mb PubMed search [3] [4]
Wikidata
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CSRP2 is a protein containing two LIM domains, which are double zinc finger motifs found in proteins of diverse function. CSRP2 and some related proteins are thought to act as protein adapters, bridging two or more proteins to form a larger protein complex. The protein encoded by this gene binds to one of the LIM domains of CSRP2 and contains an acetyltransferase domain. Although the encoded protein has been detected in the cytoplasm, it is predominantly a nuclear protein. Alternatively spliced transcript variants have been described.^[5]