CTDSP2

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 is an enzyme that in humans is encoded by the CTDSP2 gene.^[5][6][7]

CTDSP2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2Q5E
Identifiers
Aliases	CTDSP2, OS4, PSR2, SCP2, CTD small phosphatase 2
External IDs	OMIM: 608711; MGI: 1098748; HomoloGene: 128791; GeneCards: CTDSP2; OMA:CTDSP2 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q14.1 Start 57,819,927 bp[1] End 57,846,729 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10 D3|10 74.35 cM Start 126,814,586 bp[2] End 126,835,844 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gastric mucosa stromal cell of endometrium Descending thoracic aorta body of uterus left ovary right coronary artery right lung right ovary left uterine tube muscle layer of sigmoid colon Top expressed in ventricular zone lip genital tubercle zone of skin urinary bladder skeletal muscle tissue muscle of thigh esophagus uterus lung More reference expression data BioGPS More reference expression data
Gene ontology Molecular function RNA polymerase II CTD heptapeptide repeat phosphatase activity phosphatase activity protein binding phosphoprotein phosphatase activity hydrolase activity metal ion binding Cellular component nucleus nucleoplasm Biological process negative regulation of G1/S transition of mitotic cell cycle negative regulation of protein phosphorylation protein dephosphorylation IRE1-mediated unfolded protein response regulation of transcription by RNA polymerase II dephosphorylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10106 52468 Ensembl ENSG00000175215 ENSMUSG00000078429 UniProt O14595 Q8BX07 RefSeq (mRNA) NM_005730 NM_001113470 NM_146012 RefSeq (protein) NP_005721 NP_005721.3 NP_001106941 NP_666124 Location (UCSC) Chr 12: 57.82 – 57.85 Mb Chr 10: 126.81 – 126.84 Mb PubMed search [3] [4]
Wikidata
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Interactions

CTDSP2 has been shown to interact with SNAI1.^[8]