CTDSPL

CTD small phosphatase-like protein is an enzyme that in humans is encoded by the CTDSPL gene.^[5][6][7]

CTDSPL
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2HHL
Identifiers
Aliases	CTDSPL, C3orf8, HYA22, PSR1, RBSP3, SCP3, CTD small phosphatase like
External IDs	OMIM: 608592; MGI: 1916524; HomoloGene: 48881; GeneCards: CTDSPL; OMA:CTDSPL - orthologs
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3p22.2 Start 37,861,880 bp[1] End 37,984,469 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 F3 Start 118,755,521 bp[2] End 118,873,066 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in metanephric glomerulus nipple renal medulla parotid gland tibia cardia secondary oocyte pylorus skin of thigh skin of arm Top expressed in renal corpuscle right lung left lung gastrula right lung lobe medullary collecting duct left lung lobe proximal tubule retinal pigment epithelium ciliary body More reference expression data BioGPS n/a
Gene ontology Molecular function phosphatase activity phosphoprotein phosphatase activity hydrolase activity metal ion binding protein binding molecular function RNA polymerase II CTD heptapeptide repeat phosphatase activity Cellular component extracellular exosome nucleus Biological process negative regulation of G1/S transition of mitotic cell cycle negative regulation of protein phosphorylation dephosphorylation protein dephosphorylation regulation of transcription by RNA polymerase II biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10217 69274 Ensembl ENSG00000144677 ENSMUSG00000047409 UniProt O15194 P58465 RefSeq (mRNA) NM_005808 NM_001008392 NM_133710 RefSeq (protein) NP_001008393 NP_005799 NP_598471 Location (UCSC) Chr 3: 37.86 – 37.98 Mb Chr 9: 118.76 – 118.87 Mb PubMed search [3] [4]
Wikidata
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Interactions

CTDSPL has been shown to interact with SNAI1.^[8]