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Carbonic anhydrase II

Enzyme found in humans From Wikipedia, the free encyclopedia

Carbonic anhydrase II
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Carbonic anhydrase II (gene name CA2)The chemical formula is:C1324H2018O383N356S2Zn[5] is one of sixteen forms of human α carbonic anhydrases.[6] Carbonic anhydrase catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. Renal carbonic anhydrase allows the reabsorption of bicarbonate ions in the proximal tubule. [7] Loss of carbonic anhydrase activity in bones impairs the ability of osteoclasts to promote bone resorption, leading to osteopetrosis.[8]

Quick Facts CA2, Available structures ...
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Interactions

Carbonic anhydrase II has been shown to interact with band 3[9][10][11][12] and sodium-hydrogen antiporter 1.[13]

References

Further reading

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