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CatSper2

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

CatSper2
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CatSper2, is a protein which in humans is encoded by the CATSPER2 gene.[5][6] CatSper2 is a member of the cation channels of sperm family of protein. The four proteins in this family together form a Ca2+-permeant ion channel specific essential for the correct function of sperm cells.[7]

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Function

Calcium ions play a primary role in the regulation of sperm motility. This gene belongs to a family of putative cation channels that are specific to spermatozoa and localize to the flagellum. The protein family features a single repeat with six membrane-spanning segments and a predicted calcium-selective pore region. This gene is part of a tandem repeat on chromosome 15q15; the second copy of this gene is thought to be a pseudogene.[8]

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