This article is about a non-clinically used progestin compound. For the pharmaceutical drug, see
chlormadinone acetate.
Chlormadinone is a progestin which was never marketed.[1][2] An acylated derivative, chlormadinone acetate, is used clinically as a pharmaceutical drug.[1][2]
Quick Facts Clinical data, Other names ...
Chlormadinone |
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| Other names | Chlordione; 17α-Hydroxy-6-chloro-6-dehydroprogesterone; 17α-Hydroxy-6-chloropregna-4,6-diene-3,20-dione; 6-Chloro-17α-hydroxypregna-4,6-diene-3,20-dione |
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(8R,9S,10R,13S,14S,17R)-17-acetyl-6-chloro-17-hydroxy-10,13-dimethyl-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one
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| ECHA InfoCard | 100.016.185 |
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| Formula | C21H27ClO3 |
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| Molar mass | 362.89 g·mol−1 |
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| 3D model (JSmol) | |
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O=C4\C=C3\C(\Cl)=C/[C@@H]1[C@H](CC[C@@]2([C@@](O)(C(=O)C)CC[C@@H]12)C)[C@@]3(C)CC4
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InChI=1S/C21H27ClO3/c1-12(23)21(25)9-6-16-14-11-18(22)17-10-13(24)4-7-19(17,2)15(14)5-8-20(16,21)3/h10-11,14-16,25H,4-9H2,1-3H3/t14-,15+,16+,19-,20+,21+/m1/s1 Key:VUHJZBBCZGVNDZ-TTYLFXKOSA-N
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It was patented in 1958 and approved for medical use in 1963.[3] While chlormadinone is sometimes used as a synonym for chlormadinone acetate, what is almost always being referred to is chlormadinone acetate and not chlormadinone.
