Chlorophenylbiguanide

Chlorophenylbiguanide
Identifiers
	IUPAC name 2-(3-Chlorophenyl)-1-(diaminomethylidene)guanidine;
CAS Number	48144-44-1 ;
PubChem CID	1354;
IUPHAR/BPS	2287;
ChemSpider	27570 ;
UNII	910A4X901V;
ChEMBL	ChEMBL42752 ;
CompTox Dashboard (EPA)	DTXSID70197436 ;
Chemical and physical data
Formula	C8H12ClN5
Molar mass	213.67 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES c1ccc(Cl)cc1NC(=N)NC(=N)N;
	InChI InChI=1S/C8H10ClN5/c9-5-3-1-2-4-6(5)13-8(12)14-7(10)11/h1-4H,(H6,10,11,12,13,14) ; Key:MKWFJPZMYHPQIA-UHFFFAOYSA-N ;
	(verify)

meta-Chlorophenylbiguanide (1-(3-chlorophenylbiguanide, m-CPBG) is an allosteric agonist and modulator of the 5-HT₃ receptor^[1]^[2]^[3] and an antagonist of the α_2A-adrenergic receptor.^[4] It has anxiogenic, emetic and hypothermic effects in animal studies.^[5]^[6]^[7]^[8]

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See also