Choline transporter-like protein 1

Choline transporter-like protein 1 is a protein that in humans is encoded by the SLC44A1 gene.^[5][6][7]

SLC44A1
Identifiers
Aliases	SLC44A1, CD92, CDW92, CHTL1, CTL1, solute carrier family 44 member 1, CONATOC
External IDs	OMIM: 606105; MGI: 2140592; HomoloGene: 11137; GeneCards: SLC44A1; OMA:SLC44A1 - orthologs
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9q31.1-q31.2 Start 105,244,622 bp[1] End 105,439,171 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 B2 Start 53,440,413 bp[2] End 53,622,478 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in endothelial cell inferior ganglion of vagus nerve internal globus pallidus subthalamic nucleus superior vestibular nucleus external globus pallidus pars reticulata ventral tegmental area mucosa of sigmoid colon corpus epididymis Top expressed in hair follicle left colon urothelium deep cerebellar nuclei pyloric antrum transitional epithelium of urinary bladder medullary collecting duct gastric mucosa mucous cell of stomach Paneth cell More reference expression data BioGPS More reference expression data
Gene ontology Molecular function choline transmembrane transporter activity Cellular component extracellular exosome nucleoplasm mitochondrion plasma membrane integral component of membrane mitochondrial outer membrane membrane Biological process phosphatidylcholine biosynthetic process transmembrane transport choline transport choline catabolic process transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23446 100434 Ensembl ENSG00000070214 ENSMUSG00000028412 UniProt Q8WWI5 Q6X893 RefSeq (mRNA) NM_001286730 NM_022109 NM_080546 NM_001330731 NM_001159633 NM_133891 NM_001374697 RefSeq (protein) NP_001273659 NP_001317660 NP_536856 NP_001153105 NP_598652 NP_001361626 Location (UCSC) Chr 9: 105.24 – 105.44 Mb Chr 4: 53.44 – 53.62 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Papillary glioneuronal tumors characteristically exhibit a gene fusion between SLC44A1 and PRKCA.^[8][9][10] Loss of function mutations have been implicated in ethanolamine transport. ^[11]

See also

• Cluster of differentiation
• Solute carrier family