Cioteronel

Cioteronel (INNTooltip International Nonproprietary Name, USANTooltip United States Adopted Name) (developmental code name CPC-10997; former tentative brand names Cyoctol, X-Andron) is a nonsteroidal antiandrogen (NSAA) that was never marketed.^[1][2][3] It was under development between 1989 and 2001 for the topical treatment of androgenetic alopecia (male pattern baldness), and acne and for the oral treatment of benign prostatic hyperplasia; it reached phase III clinical trials for acne and phase II studies for androgenetic alopecia, but was ultimately discontinued due to poor efficacy.^[3][4]

Cioteronel

Clinical data
Other names	CPC-10997; Cyoctol; X-Andron
Routes of administration	By mouth, topical
Drug class	Nonsteroidal antiandrogen
ATC code	None
Identifiers
IUPAC name 4-(5-methoxyheptyl)-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-one
CAS Number	89672-11-7
PubChem CID	55994
ChemSpider	50555
UNII	1RTH95874Z
ChEMBL	ChEMBL2104105
CompTox Dashboard (EPA)	DTXSID50869028
Chemical and physical data
Formula	C16H28O2
Molar mass	252.398 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCC(CCCCC1CCC2C1CC(=O)C2)OC
InChI InChI=InChI=1S/C16H28O2/c1-3-15(18-2)7-5-4-6-12-8-9-13-10-14(17)11-16(12)13/h12-13,15-16H,3-11H2,1-2H3 Key:KDULJHFMZBRAHO-UHFFFAOYSA-N

See also

• Delanterone
• Inocoterone
• Metogest
• Rosterolone
• Topilutamide
• Topterone
• Zanoterone