Inocoterone

Inocoterone
Clinical data
Other names	RU-29294; 2,5-Seco-A-dinorestr-9-en-17β-ol-5-one
Routes of; administration	Topical
Drug class	Nonsteroidal antiandrogen
Identifiers
	IUPAC name (3S,3aS,9aS,9bS)-6-Ethyl-3-hydroxy-3a-methyl-2,3,4,5,8,9,9a,9b-octahydro-1H-cyclopenta[a]naphthalen-7-one;
CAS Number	83646-97-3 ; 83646-86-0 (acetate);
PubChem CID	11776794;
ChemSpider	9951477;
UNII	Q35F31B844;
CompTox Dashboard (EPA)	DTXSID10232491 ;
Chemical and physical data
Formula	C16H24O2
Molar mass	248.366 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCC1=C2CCC3(C(C2CCC1=O)CCC3O)C;
	InChI InChI=1S/C16H24O2/c1-3-10-11-8-9-16(2)13(5-7-15(16)18)12(11)4-6-14(10)17/h12-13,15,18H,3-9H2,1-2H3/t12-,13+,15+,16+/m1/s1; Key:DOTDLCMVUVGSDP-VRKREXBASA-N;

Inocoterone (INNTooltip International Nonproprietary Name; developmental code name RU-29294) is a steroid-like nonsteroidal antiandrogen (NSAA) that was never marketed.^[1]^[2] An acetate ester, inocoterone acetate, shows greater antiandrogen activity and was developed, as a topical medication for the treatment of acne but showed only modest effectiveness in clinical trials and similarly was never marketed.^[3]

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See also