Coiled-coil domain containing 88b

Coiled-coil domain containing 88B is a protein that in humans is encoded by the CCDC88B gene. ^[5]

CCDC88B
Identifiers
Aliases	CCDC88B, BRLZ, CCDC88, HKRP3, gipie, coiled-coil domain containing 88B
External IDs	OMIM: 611205; MGI: 1925567; HomoloGene: 49992; GeneCards: CCDC88B; OMA:CCDC88B - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q13.1 Start 64,340,204 bp[1] End 64,357,534 bp[1]
Gene location (Mouse) Chr. Chromosome 19 (mouse)[2] Band 19|19 A Start 6,821,991 bp[2] End 6,835,579 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte cerebellar hemisphere right hemisphere of cerebellum spleen appendix monocyte bone marrow cell blood mucosa of transverse colon lymph node Top expressed in granulocyte thymus mesenteric lymph nodes neural layer of retina spermatocyte spermatid bone marrow spleen blood seminiferous tubule More reference expression data BioGPS n/a
Gene ontology Molecular function microtubule binding dynein light intermediate chain binding Cellular component membrane cytoplasm endoplasmic reticulum Golgi apparatus centrosome cytoskeleton Biological process positive regulation of T cell activation positive regulation of T cell proliferation positive regulation of cytokine production defense response to protozoan cytoskeleton-dependent intracellular transport cytoplasmic microtubule organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 283234 78317 Ensembl ENSG00000168071 ENSMUSG00000047810 UniProt A6NC98 Q4QRL3 RefSeq (mRNA) NM_032251 NM_001081291 NM_198008 RefSeq (protein) NP_115627 NP_001074760 Location (UCSC) Chr 11: 64.34 – 64.36 Mb Chr 19: 6.82 – 6.84 Mb PubMed search [3] [4]
Wikidata
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Function

This gene encodes a member of the hook-related protein family. Members of this family are characterized by an N-terminal potential microtubule binding domain, a central coiled-coiled and a C-terminal Hook-related domain. The encoded protein may be involved in linking organelles to microtubules. [provided by RefSeq, Oct 2009].