Cyclin E2

Cyclin E2 is a protein that in humans is encoded by the CCNE2 gene. It is a G1 cyclin that binds Cdk2 and is inhibited by p27(Kip1) and p21(Cip1).^[1] It plays a role in the G1/S portion of the cell cycle and also has putative interactions with proteins CDKN1A, CDKN1B, and CDK3. Aberrant expression can lead to cancer.^[1]

cyclin E2
Identifiers
Symbol	CCNE2
NCBI gene	9134
HGNC	1590
OMIM	603775
RefSeq	NM_057749
UniProt	O96020
Other data
Locus	Chr. 8 q22.1
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