Cycloproscaline

Cycloproscaline
Clinical data
Other names	CP; 4-Cyclopropoxy-3,5-dimethoxyphenethylamine; 4-cPrO-3,5-DMPEA
Routes of; administration	Oral
Drug class	Serotonin receptor modulator; Serotonin 5-HT2A receptor agonist; Serotonergic psychedelic; Hallucinogen
ATC code	None;
Pharmacokinetic data
Duration of action	≥6 hours
Identifiers
	IUPAC name 2-(4-cyclopropyloxy-3,5-dimethoxyphenyl)ethanamine;
CAS Number	2375260-81-2;
PubChem CID	145874427;
ChemSpider	77003461;
Chemical and physical data
Formula	C13H19NO3
Molar mass	237.299 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES COC1=CC(=CC(=C1OC2CC2)OC)CCN;
	InChI InChI=1S/C13H19NO3/c1-15-11-7-9(5-6-14)8-12(16-2)13(11)17-10-3-4-10/h7-8,10H,3-6,14H2,1-2H3; Key:VRTSLAVKWTZKIT-UHFFFAOYSA-N;

Cycloproscaline (CP), also known as 4-cyclopropoxy-3,5-dimethoxyphenethylamine (4-cPrO-3,5-DMPEA), is a psychedelic drug of the phenethylamine and scaline families related to mescaline.^[1]^[2] It is the homologue of mescaline in which the 4-methoxy group has been replaced with a 4-cyclopropoxy group.^[1]^[2] The drug has a dose of 60 mg or more orally and a duration of 6 hours or more, but has not been fully evaluated.^[1]^[2] It is a low-potency full agonist of the serotonin 5-HT_2A receptor and also interacts with other serotonin receptors such as the serotonin 5-HT_1A and 5-HT_2C receptors.^[2] The drug's chemical synthesis has been described.^[1] Cycloproscaline was first described in the scientific literature by Daniel Trachsel and colleagues in 2013.^[1] Its pharmacology was studied in greater detail in 2021.^[2]

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See also