DAPP1

Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide is a protein that in humans is encoded by the DAPP1 gene.^[5][6]

DAPP1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1FAO, 1FB8
Identifiers
Aliases	DAPP1, BAM32, dual adaptor of phosphotyrosine and 3-phosphoinositides, dual adaptor of phosphotyrosine and 3-phosphoinositides 1
External IDs	OMIM: 605768; MGI: 1347063; HomoloGene: 32138; GeneCards: DAPP1; OMA:DAPP1 - orthologs
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4q23 Start 99,816,827 bp[1] End 99,870,190 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 G3 Start 137,636,768 bp[2] End 137,687,306 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in amniotic fluid epithelium of nasopharynx monocyte buccal mucosa cell mucosa of paranasal sinus oral cavity epithelium of bronchus bronchial epithelial cell palpebral conjunctiva sperm Top expressed in epithelium of small intestine granulocyte spermatocyte seminiferous tubule spermatid blood zygote conjunctival fornix tibiofemoral joint bone marrow More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding phospholipid binding phosphatidylinositol-3,4,5-trisphosphate binding phosphatidylinositol-3,4-bisphosphate binding PDZ domain binding Cellular component cytosol plasma membrane membrane cytoplasm Biological process protein dephosphorylation signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 27071 26377 Ensembl ENSG00000070190 ENSMUSG00000028159 UniProt Q9UN19 Q9QXT1 RefSeq (mRNA) NM_001306151 NM_014395 NM_011932 NM_001310753 RefSeq (protein) NP_001293080 NP_055210 NP_001297682 NP_036062 Location (UCSC) Chr 4: 99.82 – 99.87 Mb Chr 3: 137.64 – 137.69 Mb PubMed search [3] [4]
Wikidata
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